Further evidence for the presence of androgen receptors in the lungs and in the head appendages of the cock

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Abstract
The presence of cytoplasmic dihydrotestosterone receptors in the lungs, the comb, the wattle and the ear lobes of the cock was demonstrated by sucrose density-gradient centrifugation. All these tissues exhibited saturable in vitro binding of dihydrotestosterone in the 8-11S region of the gradient. When 0.5 M KCl was added to the lung, wattle, and comb cytosols and to the gradients, the radioactive dihydrotestosterone migrated in the 4-5S region. The mechanism of action of androgens in the head appendages of the cock and in other target tissues is probably similar.

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