Effects of age and substrate on the circadian rhythm of liver tryptophan pyrrolase of female rats
- 1 May 1980
- journal article
- Published by Wiley in Cell Biology International Reports
- Vol. 4 (5) , 471-477
- https://doi.org/10.1016/0309-1651(80)90034-x
Abstract
The level of tryptophan pyrrolase does not change significantly throughout the 24 hr cycle of the day in rat liver. Young and adult rats show a similar trend in the activity pattern of this enzyme. However, the activity pattern is altered in the post-reproductive rats. L-tryptophan induces liver tryptophan pyrrolase in rats of all the ages. Maximum induction is observed in the post-reproductive rats as compared to the young and adult rats. Further, the degree of induction of this enzyme by its substrate is also affected by the age of the rat.Keywords
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