New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. II. Structure of 2-hydroxyaklavinone and new aklavinone glycosides.
- 1 January 1981
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 34 (8) , 959-964
- https://doi.org/10.7164/antibiotics.34.959
Abstract
Four blocked mutants of aclacinomycin-producing S. galilaeus MA144-M1 produced new anthracyclinones; 2-hydroxyaklavinone, its non-esterified analog and 2-hydroxy-7-deoxyaklavinone, several new anthracyclines; 2-deoxyfucosyl-2-deoxyfucosyl-rhodosaminylaklavinone (MA144 U1), 2-deoxyfucosyl-rhodosaminylaklavinone (MA144 U2) and 5 aklavinone glycosides devoid of amino sugar, designated as MA144 U5, U6, U7, U8 and U9.This publication has 3 references indexed in Scilit:
- New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. I. Isolation and characterization of various blocked mutants.The Journal of Antibiotics, 1981
- Antitumor anthracycline antibiotics, aclacinomycin A and analogues. II. Structural determination.The Journal of Antibiotics, 1979
- Antitumor anthracycline antibiotics, aclacinomycin A and analogues. I. Taxonomy, production, isolation and physicochemical properties.The Journal of Antibiotics, 1979