Excitatory neuromuscular transmission in crayfish: Calcium dependence is unaffected by picrotoxin

Publisher Website
Google Scholar
Abstract
Picrotoxin, 1 × 10−5M to 1.6 × 10−3M, had little or no effect on the amplitude of intracellularly recorded excitatory junctional potentials (EJPs) at extracellular calcium concentrations [Ca2+]0 ranging from 0.5 to 15 mM. The slope of the log EJP vs. log[Ca2+]0 relationship was approximately 1 with or without picrotoxin. The reduction of EJP amplitude resulting from the addition of 5 × 10−5M GABA was largely reversed by 10−5M picrotoxin.