Melatonin protects against 6‐OHDA‐induced neurotoxicity in rats: a role for mitochondrial complex I activity
Open Access
- 9 November 2000
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 15 (1) , 164-170
- https://doi.org/10.1096/fj.00-0129com
Abstract
Unilateral injection into the right substantia nigra of the catecholaminergic neurotoxin 6-hydroxydopamine (6-OHDA) produces extensive loss of dopaminergic cells (‘hemi-parkinsonian rat’). The pineal...Keywords
This publication has 64 references indexed in Scilit:
- ETIOLOGY AND PATHOGENESIS OF PARKINSON'S DISEASEAnnual Review of Neuroscience, 1999
- Oxidative stress and antioxidant therapy in Parkinson's diseaseProgress in Neurobiology, 1996
- Reactive Oxygen Species Influence Nerve Growth Factor Synthesis in Primary Rat AstrocytesJournal of Neurochemistry, 1994
- The determination of hydroxydopamines and other trace amines in the urine of Parkinsonian patients and normal controlsNeurochemical Research, 1993
- Oxidative Stress, Glutamate, and Neurodegenerative DisordersScience, 1993
- On-off effects of dopamine receptor agonists in the hemi-parkinsonian ratEuropean Journal of Pharmacology, 1993
- Partial lesion of the substantia nigra: relation between extent of lesion and rotational behaviorBrain Research, 1991
- Turning behaviour in animalsNeuroscience, 1980
- Neuropharmacological studies on D145 (1,3-dimethyl-5-aminoadamantan)Psychopharmacology, 1975
- Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine SystemActa Physiologica Scandinavica, 1971