Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells
- 15 July 1999
- Vol. 86 (2) , 300-311
- https://doi.org/10.1002/(sici)1097-0142(19990715)86:2<300::aid-cncr14>3.0.co;2-h
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.Journal of Clinical Investigation, 1997
- Ceramide: A Novel Lipid Mediator of ApoptosisPublished by Elsevier ,1997
- Agents that Reverse Multidrug Resistance, Tamoxifen, Verapamil, and Cyclosporin A, Block Glycosphingolipid Metabolism by Inhibiting Ceramide Glycosylation in Human Cancer CellsJournal of Biological Chemistry, 1997
- Accumulation of Glucosylceramides in Multidrug-resistant Cancer CellsJournal of Biological Chemistry, 1996
- Glucosylceramides stimulate murine epidermal hyperproliferation.Journal of Clinical Investigation, 1995
- Interaction of tamoxifen with the multidrug resistance P-glycoproteinBritish Journal of Cancer, 1995
- Cell Cycle Arrest Induced by an Inhibitor of Glucosylceramide SynthaseJournal of Biological Chemistry, 1995
- P-glycoprotein, multidrug resistance and tumor progressionCancer and Metastasis Reviews, 1994
- Expression of resistance factors (P-glycoprotein, glutathione S-transferase-π, and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinomasCancer, 1993
- BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTERAnnual Review of Biochemistry, 1993