POLYMORPHISM OF NEAR-CENTROMERIC HETEROCHROMATIN IN POPULATION OF HEALTHY HUMANS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 12  (4) , 136-141
Abstract
Polymorphism of constitutive heterochromatin of metaphase chromosomes 1, 9 and 16 in 6 normal humans (both men and women) is studied by means of C-staining. Only slight variability in size of C-blocks in 1 individual (from cell to cell) and a high frequency of C-chromatin heteromorphism variants within the population studied is observed. Variants of C-heterochromatin (8) (heteromorphic homologues) are found: 4 individuals had 1-2 variants and 1 individual, 3 variants. Quantitative analysis based on measurements of C-blocks confirmed the reliability of the existence of these variants.

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