RESPIRATION AND GLYCOLYSIS OF FOCAL EPILEPTOGENIC HUMAN BRAIN TISSUE

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Abstract
Samples of brain excised surgically from patients suffering from focal epilepsy were studied. The avg. respiration rates of gray slices in bicarbonate buffered saline medium and in Ca-free phosphate buffered saline medium were not significantly different from the rates predicted in the preceding paper for normal human brain tissue. Variability in the rates with different samples showed no correlation with the certainty with which the tissue was rated as epileptogenic. The ratios of respiratory CO2 production, aerobic and anaerobic glycolytic activity to the oxygen uptake of suspensions and slices were within the range of those found for brain tissue from large normal animals.

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