Immunohistochemical Localization of Carcinoembryonic Antigen in Microglandular Hyperplasia and Adenocarcinoma of the Endocervix
Open Access
- 1 January 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 79 (1) , 105-107
- https://doi.org/10.1093/ajcp/79.1.105
Abstract
Immunoperoxidase localization of carcinoembryonic antigen (CEA) was performed on tissue sections of microglandular hyperplasia and adenocarcinoma of endocervical origin to see if CEA would be a marker of malignancy in this context. Twenty (95%) of 21 of the benign lesions were negative and one was focally positive. Nine (64%) of 14 adenocarcinomas were widely positive, four were focally positive, and one was negative. These results suggest that extensive immunohistochemical positivity for CEA in endocervical glandular lesions is indicative of malignancy.Keywords
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