Abstract
In 3 control dogs in which salt solution was injected under the skin, there was a slight increase in the volume of plasma, practically no alteration in the concentration and an increase in the absolute amts. of the protein constituents. Trauma to the intestines and subcutaneous injection of histamine in 3 experiments each were associated with a decrease in the volume of plasma, no definite change in the concentration of total protein, albumin and globulin and a marked decrease in the absolute amts. of the protein constituents. A smaller amt. of the salt solution was absorbed by the circulation in these experiments than in the others. The graded removal of blood in 3 dogs was associated with a decrease in the concentration of the red blood cells, a slight diminution in the percentages of total protein, albumin and globulin in the blood serum, and an increase in the absolute amts. of the protein constituents if the amount of protein removed is included.

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