Synthetic approaches to the alkaloids of the ancistrocladaceae: control of the diastereoisomer excess in the synthesis of axially chiral biaryls: a synthesis of (–)-ancistrocladinine
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 5,p. 278-280
- https://doi.org/10.1039/c39910000278
Abstract
An attempt is made to delineate the factors which control the diastereoisomeric excess in the reactions of 2,6-disubstituted phenyl Grignard reagents with the naphthyloxazoline 2; advantage is taken of the results in a synthesis of the Ancistrocladus alkaloid (–)-ancistrocladinine 19.Keywords
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