A Conserved Docking Site in MEKs Mediates High-affinity Binding to MAP Kinases and Cooperates with a Scaffold Protein to Enhance Signal Transmission

This publication has 93 references indexed in Scilit:

• Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway
  Genes & Development, 1998
• Anthrax Lethal Factor Cleaves the N-Terminus of MAPKKs and Induces Tyrosine/Threonine Phosphorylation of MAPKs in Cultured Macrophages
  Biochemical and Biophysical Research Communications, 1998
• The structural basis for substrate recognition and control by protein kinases¹
  FEBS Letters, 1998
• Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11
  Current Biology, 1998
• Structure-Function Studies of p38 Mitogen-activated Protein Kinase
  Journal of Biological Chemistry, 1997
• KSR modulates signal propagation within the MAPK cascade.
  Genes & Development, 1996
• Mammalian Mitogen-activated Protein Kinase Pathways Are Regulated through Formation of Specific Kinase-Activator Complexes
  Journal of Biological Chemistry, 1996
• Identification of MAP Kinase Domains by Redirecting Stress Signals into Growth Factor Responses
  Science, 1996
• Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
  Nature, 1995
• Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae
  Cell, 1994