Spectroscopic study of the interaction between poly‐(9‐vinyladenine) and single or multistrand RNA
- 1 July 1992
- journal article
- research article
- Published by Wiley in Biopolymers
- Vol. 32 (7) , 811-817
- https://doi.org/10.1002/bip.360320709
Abstract
The interaction between poly(9‐vinyladenine) (PVAd) and poly[r (U)] was investigated by means of uv, CD, 1H‐, and 31P‐nmr spectroscopies. The interaction was dependent on the molecular weight of PVAd determined by uv and CD spectroscopies. Based on imino proton nmr, it was clearly found that PVAd formed the complex with poly [r(U)] by complementary hydrogen bonding. The interaction of PVAd with double‐ and triple‐stranded helices of RNA was also investigated by uv melting behavior and 31P‐nmr spectroscopy. The results suggested that PVAd could not interact with the double‐stranded poly [r (A)] · poly[r(U)] but did with the triple‐stranded RNA.Keywords
This publication has 19 references indexed in Scilit:
- Asymmetric polymerization of methacrylatesProgress in Polymer Science, 1990
- Agarose-Poly(9-vinyladenine) Conjugated Gel. Application for Electrophoretic Separation of Nucleic AcidsChemistry Letters, 1990
- Review : Polynucleotides as Interferon Inducers and Immune ModulatorsJournal of Bioactive and Compatible Polymers, 1986
- Solvent suppression in fourier transform nuclear magnetic resonanceJournal of Magnetic Resonance (1969), 1983
- Nonequivalence of phosphorus-31 NMR chemical shifts of RNA complexesJournal of the American Chemical Society, 1981
- Vinyl polymer analogues of nucleic acidsPolymer, 1977
- Cooperative nonenzymic base recognition II. thermodynamics of the helix‐coil transition of oligoadenylic + oligouridylic acidsBiopolymers, 1971
- Antiviral Resistance by the Polyinosinic Acid-Poly(1-vinylcytosine) ComplexScience, 1971
- Nucleic acid analogs. Interaction of poly-9-vinyladenine with polyuridylic acidJournal of the American Chemical Society, 1970
- Circular dichroism of polynucleotides: A simple theoryBiopolymers, 1969