Synthesis, Corticotropin-Releasing Factor Receptor Binding Affinity, and Pharmacokinetic Properties of Triazolo-, Imidazo-, and Pyrrolopyrimidines and -pyridines
- 17 February 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 42 (5) , 833-848
- https://doi.org/10.1021/jm980224g
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Non-Peptide Corticotropin-Releasing Hormone Antagonists: Syntheses and Structure−Activity Relationships of 2-Anilinopyrimidines and -triazinesJournal of Medicinal Chemistry, 1999
- Stress-induced immune suppression: Role of brain corticotropin releasing hormone and autonomic nervous system mechanismsAdvances in Neuroimmunology, 1994
- The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: Implications for a role for CRF in the pathogenesis of anxiety disordersJournal of Psychiatric Research, 1993
- Hypercortisolism Among Socially Subordinate Wild Baboons Originates at the CNS LevelArchives of General Psychiatry, 1989
- A molecular basis for bidirectional communication between the immune and neuroendocrine systems.Physiological Reviews, 1989
- A corticotropin-releasing factor antagonist reverses the stress-induced changes of exploratory behavior in miceHormones and Behavior, 1987
- Corticotropin-releasing factor elicits naloxone sensitive stress-like alterations in exploratory behavior in miceRegulatory Peptides, 1986
- Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressinNature, 1983
- Intraventricular corticotropin-releasing factor enhances behavioral effects of noveltyLife Sciences, 1982
- Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-EndorphinScience, 1981