Metabolism of daunorubicin by a barbiturate-sensitive aldehyde reductase from rat liver
- 1 December 1976
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 159 (3) , 819-822
- https://doi.org/10.1042/bj1590819
Abstract
A barbiturate-sensitive aldehyde reductase was purified to homogeneity from rat liver and shown to metabolize the cancer-chemotherapeutic antibiotic daunorubicin. The aldehyde reductase may have important roles in the metabolism of exogeneous drugs as well as the aldehyde derivatives of the biogenic amines.This publication has 15 references indexed in Scilit:
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