HISTOCLINICAL LONG-STANDING FOLLOW-UP-STUDY OF HYPERPLASTIC POLYPS OF THE STOMACH

  • 1 January 1981
    • journal article
    • research article
    • Vol. 75  (4) , 275-281
Abstract
In a series of 2013 gastric polyps in 1201 patients, morphological and histopathological studies were performed. Hyperplastic polyps (93) in 56 patients were followed-up endoscopically and histopathologically for 5-12 yr. The incidence of detection of gastric polyps has increased: 1.4% in 1967 to 8.7% in 1979, year by year. Patients (30; 54%) among the 56 showed changes in number, size or shape of polyps during follow-up. Twenty patients (37%) revealed numerical changes (increase in 16 patients, reversion in 3 patients and vanishing in 2 patients). Polyps (29; 30%) showed morphological changes: 6 of them showed continuous enlargement; 18 lesions repeated enlargement, stationary or reduction stages; 3 lesions were reversed, and 2 polyps disappeared. Histopathologically, 3 lesions showed transformation from the hyperplastic type to adenoma while demonstrating morphological enlargement. Two of these showed increase in cellular atypia from the hyperplastic type through adenoma with severe atypia, and finally to carcinoma in the polypectomy specimens. Although hyperplastic polyps show changes in size, shape or number with passage of time, malignant changes evidently occur in only a few cases.