An Evaluation of Cognitive-Behaviour Therapy for Depression in Patients with Multiple Sclerosis

Abstract
Depressed multiple sclerotic patients (20) were randomly allocated to cognitive-behavior therapy or to a waiting list control condition. Assessment of depressive symptoms was conducted at pretreatment, posttreatment and a 4-wk follow-up. In comparison to the waiting list control condition, cognitive-behavior therapy resulted in clinically and statistically significant improvement on most measures. Although the mecanism by which such treatment achieves its effects is unclear, these results clearly support the use of cognitive-behavioral treatments for depression in this population.

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