Drug-mediated toxicity caused by genetic deficiency of UDP-glucuronosyltransferases
- 1 March 2000
- journal article
- review article
- Published by Elsevier in Toxicology Letters
- Vol. 112-113, 333-340
- https://doi.org/10.1016/s0378-4274(99)00209-x
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.Journal of Clinical Investigation, 1998
- Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepamPharmacogenetics, 1995
- (S )Oxazepam glucuronidation is inhibited by Ketoprofen and other substrates of UGT2B7Pharmacogenetics, 1995
- Disposition of Lorazepam in Gilbert's Syndrome: Effects of Fasting, Feeding, and Enterohepatic CirculationThe Journal of Clinical Pharmacology, 1994
- Human UDP‐glucuronosyl transferases: Chemical defence, jaundice and gene therapyBioEssays, 1993
- Expression of a human liver cDNA encoding a UDP‐glucuronosyltransferase catalysing the glucuronidation of hyodeoxycholic acid in cell cultureFEBS Letters, 1989
- Normal pathways for glucuronidation, sulphation and oxidation of paracetamol in Gilbert's syndromeEuropean Journal of Clinical Investigation, 1987
- Pathogenesis of Gilbert's syndromeEuropean Journal of Clinical Investigation, 1981
- Gilbert??s Syndrome and Drug MetabolismClinical Pharmacokinetics, 1979
- Unconjugated Bilirubin and an Increased Proportion of Bilirubin Monoconjugates in the Bile of Patients with Gilbert's Syndrome and Crigler-Najjar DiseaseJournal of Clinical Investigation, 1977