FURTHER STUDIES ON THE REACTION BETWEEN HALOGEN-SUBSTITUTED NITRILES AND AMINES
- 1 April 1961
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 39 (4) , 761-764
- https://doi.org/10.1139/v61-092
Abstract
The scope of the reaction of halogen-substituted nitriles and amines was extended by including trifluoro- and dichloro-acetonitrile. Trifluoroacetonitrile reacts easily with primary and secondary aliphatic, primary aromatic, and heterocyclic amines to give the corresponding amidines. N-Mono- and N-di-substituted dichloroacetamidines were prepared from dichloro-acetonitrile and amines, Trichloroacetonitrile also affords N-substituted amidines with heterocyclic amines.Keywords
This publication has 1 reference indexed in Scilit:
- Reactions of Perfluoronitriles. I. Synthesis of Derivatives of Perfluoroamidines, N-Substituted Perfluoroamidines and Perfluorothioamides1,2Journal of the American Chemical Society, 1956