Epigenetic regulation of chromatin structure and gene function by biotin: are biotin requirements being met?
- 29 July 2008
- journal article
- review article
- Published by Oxford University Press (OUP) in Nutrition Reviews
- Vol. 66 (suppl_1) , S46-S48
- https://doi.org/10.1111/j.1753-4887.2008.00073.x
Abstract
Histones H2A, H3, and H4 are modified by covalent binding of the vitamin biotin to distinct lysine residues. Binding of biotin to histones is mediated by holocaKeywords
This publication has 22 references indexed in Scilit:
- Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locusThe Journal of Nutritional Biochemistry, 2008
- K12-biotinylated histone H4 marks heterochromatin in human lymphoblastoma cellsThe Journal of Nutritional Biochemistry, 2007
- An avidin-based assay for histone debiotinylase activity in human cell nucleiThe Journal of Nutritional Biochemistry, 2007
- K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidaseThe FEBS Journal, 2005
- Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidaseThe Journal of Nutritional Biochemistry, 2005
- Biotin deficiency decreases life span and fertility but increases stress resistance in Drosophila melanogasterThe Journal of Nutritional Biochemistry, 2004
- K8 and K12 are biotinylated in human histone H4European Journal of Biochemistry, 2004
- Reduced histone biotinylation in multiple carboxylase deficiency patients: a nuclear role for holocarboxylase synthetaseHuman Molecular Genetics, 2003
- Translating the Histone CodeScience, 2001
- Conflicting indicators of biotin status from a cross-sectional study of normal pregnancy.Journal of the American College of Nutrition, 1997