Inclusion Body Myositis and Sjogren's Syndrome

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Abstract
The association of inclusion body myositis (IBM) with disorders having immune abnormalities has been reported recently.1-3 We describe a patient with IBM and Sjögren's syndrome. REPORT OF A CASE A 70-year-old woman presented with a ten-year history of progressive muscle weakness. A trial of prednisone, 60 mg daily, for several months in 1981 was without benefit. By October 1983, she was unable to climb stairs and required assistance when walking. She had no bulbar symptoms. Since 1971, she has had dry eyes and mouth and had a total removal of the left parotid gland for "infection." In recent years she has also had cold-induced blanching of her fingers. General physical examination showed only a grade 3/6 apical systolic murmur. Weakness was prominent in quadriceps and iliopsoas muscles. Mild weakness was present in other proximal and distal muscles of all four extremities and in facial and tongue muscles. Gowers' sign