Oral Cholecystography with Iopanoic Acid

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Abstract
GALLBLADDER disease is an enormous medical problem in the United States. It has been estimated that 15 million Americans have gallstones and that approximately one third of a million require cholecystectomy each year at a cost approaching half a billion dollars.1 The principal method for the detection of this prevalent disorder is oral cholecystography, and the contrast material most frequently employed for this purpose is iopanoic acid.* More than 40 million doses of this compound have been administered since its introduction as an oral cholecystographic agent 20 years ago.A major shortcoming of iopanoic acid is its failure to produce . . .

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