Efficient Proline-Catalyzed Michael Additions of Unmodified Ketones to Nitro Olefins
Top Cited Papers
- 14 July 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 3 (16) , 2423-2425
- https://doi.org/10.1021/ol015799d
Abstract
Here we describe the proline-catalyzed Michael addition of unmodified ketones to nitro olefins. This novel reaction provides γ-nitro ketones in modest enantioselectivity yet excellent yields.Keywords
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