The Role of Ether Anesthesia in the Production of Influenza Virus Pneumonia in Mice
Open Access
- 1 November 1945
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 51 (5) , 355-357
- https://doi.org/10.4049/jimmunol.51.5.355
Abstract
Summary: Swine influenza virus pneumonia of equal extent was produced in two groups of mice, one group having been anesthetized with ether and the other with nembutal administered intraperitoneally. This suggests that the insusceptibility of unanesthetized animals to influenza virus is to be explained merely on the basis of their failure to aspirate the virus. The ease with which viral pneumonia is produced in animals under ether anesthesia is to be referred to the ready aspiration of the viral suspension by the unconscious animals rather than to an increased susceptibility of the respiratory mucosa produced by ether.Keywords
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