Monte Carlo calculation of dose enhancement by neutron capture of10B in fast neutron therapy

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Abstract
The slowing down of the fast neutrons, resulting in a thermal neutron distribution of a phantom, has been computed using a Monte Carlo model. This model, which includes a deep-seated tumour, was experimentally verified by measurements of the thermal neutron fluence rate in a phantom using neutron activation of gold foil. When non-boronated water phantoms were irradiated with a total dose of 1 Gy at a depth of 6 cm, the thermal fluencies at this depth were found to be 2*1010 cm-2. The absorbed dose in a tumour with 100 ppm 10B, at the same depth was enhanced by 15%.