AN UNUSUAL TYPE OF HYPOKALAEMIC ALKALOSIS WITH A DISTURBANCE OF RENIN AND ALDOSTERONE

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Abstract
3 patients with an unusual type of hypokalaemic alkalosis are described. The findings in these patients are compared with those in similar cases reported by Bartter and others (Bartter's syndrome). It is stressed that all of the abnormalities found in Bartter's syndrome may occur in sodium deficiency in the absence of organic disease. The pathogenesis of the syndrome in our patients is uncertain but several possibilities are discussed. These include an apparently new aetiological hypothesis, a partial block in the adrenocortical response to stimulation by angiotensin.

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