A rat-tissue aminotransferase acting on l-tyrosine O-sulphate

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Abstract
Rat tissues have been shown to possess an aminotransferase that is active towards L-tyrosine O-sulphate and dependent on 2-oxoglutarate and pyridoxal phosphate. Kidney, liver and pancreas have the greatest activity and the enzyme is localized mainly in the mitochondri-al fraction in the liver and kidney cell. The enzyme was shown to be distinct from L-tyrosine-2-oxoglutarate aminotransferase but its true identity was not established. A procedure for the assay of the enzyme in crude tissue preparations was developed.