Facile synthesis of 7-amino-4-carbamoylmethylcoumarin (ACC)-containing solid supports and their corresponding fluorogenic protease substrates.

This publication has 13 references indexed in Scilit:

• Synthesis and enzymatic evaluation of a P1 arginine aminocoumarin substrate library for trypsin-like serine proteases
  Bioorganic & Medicinal Chemistry Letters, 2000
• Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries
  Proceedings of the National Academy of Sciences, 2000
• Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin
  Nature Biotechnology, 2000
• Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
  Chemical Reviews, 1999
• Recent developments in HIV protease inhibitor therapy
  Antiviral Research, 1998
• A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
  Journal of Biological Chemistry, 1997
• A combinatorial approach for determining protease specificities: application to interleukin-1β converting enzyme (ICE)
  Chemistry & Biology, 1997
• Origins of the specificity of tissue-type plasminogen activator.
  Proceedings of the National Academy of Sciences, 1995
• Substrate Phage: Selection of Protease Substrates by Monovalent Phage Display
  Science, 1993
• Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrates
  Analytical Biochemistry, 1977