Age-Related Differences in Internal Prostatic Architecture on Transrectal Ultrasonography: Results of a Community Based Survey in Japan

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Abstract
Purpose: We determined age-related differences in prostate internal architecture and prostate volume by transrectal ultrasonography in Japanese men 40 to 79 years old. Materials and Methods: The 287 study participants were categorized by transition zone disease: group 1-not visible (normal prostate), group 2-visible, borders unclear (diffusely enlarged hyperplasia) and group 3-visible, border clear (nodularly enlarged hyperplasia). Results: Group 1 comprised 40% of men 50 to 79 years old and showed slightly decreased median prostate volume with age. Prostate volume and its variance increased with age in group 3 but differed little across age in group 2. Conclusions: In a community sample the prostatic internal architecture relationship with age and prostate volume suggested differing growth patterns.