Comparison of clinical and pathological features in African-American and Caucasian patients with localized prostate cancer

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Abstract
Tumour involvement, and specimen weight. African-American and Caucasian patients were compared for PSA, clinical stage, pathological stage, biopsy and pathological Gleason grade, organ confinement, margin status and specimen weight. Using preoperative and pathological data, both groups were also compared for over- and under-staging and -grading. The Wilcoxon rank test with P < 0.05 was used to determine statistically significant differences. RESULTS African-American patients were more likely to be Medicaid or self-insured than Caucasian patients. Age, biopsy grade and clinical stage were not significantly different between the groups. African-American patients presented with a mean PSA level of 11.9 ng/mL and Caucasians with a mean of 8.5 ng/mL ( P = 0.03). When clinical and biopsy data were compared with pathological data there were no differences between the groups in under/ over-grading or under/over-staging. African- American patients had larger prostates per