Human Proinsulin, V. Synthesis of a Protected Peptide Fragment Corresponding to the Sequence 24-45 of the Prohormone
- 1 January 1980
- journal article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 361 (1) , 849-856
- https://doi.org/10.1515/bchm2.1980.361.1.849
Abstract
The protected peptide fragment 24-45 of human proinsulin, Bpoc-Phe-Phe-Tyr(But)-Thr-(But)-Pro-Lys(Boc)-Thr(But)-Arg(H2SO4)-Arg-(H2SO4)-Gl u(OBut)-Ala-Glu(OBut)-Asp(OBut)-Leu-Gln-Val-Gly-Gin-Val-Glu(OBut)-Leu-Gly-Oh, was synthesized from the two intermediate fragments 24--33 and 34--45, and purified by countercurrent distribution in the carbon tetrachloride system (K = 2.5).Keywords
This publication has 2 references indexed in Scilit:
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- Reinvestigation of the mixed carbonic anhydride method of peptide synthesisJournal of the American Chemical Society, 1967