Oral Facial Dyskinesia Associated with Prolonged Use of Antihistaminic Decongestants

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Abstract
ANTIHISTAMINIC-sympathomimetic drug combinations, widely used for symptomatic treatment of upper-respiratory-tract congestion, are considered to have few serious side effects. In the following cases persistent involuntary movements of the face and mouth were associated with use of medications of this type.Case 1. A 55-year-old housewife with recurrent rhinitis had taken two medications on a regular basis for 10 years. The first of these was a timed-release capsule containing brompheniramine maleate, 12 mg, phenylephrine hydrochloride, 15 mg, and phenylpropanolamine hydrochloride 15 mg. She took two tablets a day for eight years, and then took two tablets every other day. The other . . .

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