Chemical Evolution from Hydrogen Cyanide: Photochemical Decarboxylation of Orotic Acid and Orotate Derivatives
- 28 July 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 201 (4353) , 361-362
- https://doi.org/10.1126/science.208152
Abstract
Irradiation of solutions at p H 7 to p H 8.5 of orotic acid, orotidine, and orotidine 5′-phosphate with light at 254 nanometers yields the corresponding uracil derivative via the singlet excited state. This reaction completes a plausible prebiotic synthesis of uracil and its derivatives starting from HCN as the only carbon source.This publication has 14 references indexed in Scilit:
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