Cloning and sequence analysis of pituitary cDNA encoding the β‐subunit of Xenopus proteasome
- 7 October 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 291 (1) , 37-40
- https://doi.org/10.1016/0014-5793(91)81098-s
Abstract
The proteasome is a multicatalytic proteinase composed of a number of non-identical subunits. A Xenopus pituitary cDNA was isolated and found to code for the β-subunit of proteasome. The amino acid sequence deduced from the open reading frame consisted of 215 amino acid residues with a calculated molecular weight of 23 979. A comparative structural analysis indicated that the proteasome subunits can be divided into two groups with the same evolutionary origin. One group consists of subunits with an N-terminally blocked residue and includes components C2, C3, C8 and C9, while the second group of non-blocked proteins includes components C5 and the β-subunit.Keywords
This publication has 22 references indexed in Scilit:
- Cloning and sequencing of the gene encoding the large (α‐) subunit of the proteasome from Thermoplasma acidophilumFEBS Letters, 1991
- cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cellsBiochemical and Biophysical Research Communications, 1990
- cDNA cloning and sequencing of component C9 of proteasomes from rat hepatoma cellsFEBS Letters, 1990
- cDNA cloning and sequencing of component C5 of proteasomes from rat hepatoma cellsFEBS Letters, 1990
- Molecular cloning of cDNA for proteasomes from rat liver: primary structure of component C3 with a possible tyrosine phosphorylation siteBiochemistry, 1990
- Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome)Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1990
- The Drosophila PROS-28.1 gene is a member of the proteasome gene familyGene, 1990
- The latent form of macropain (high molecular weight multicatalytic protease) restores ATP-dependent proteolysis to soluble extracts of BHK fibroblasts pretreated with anti-macropain antibodiesBiochemical and Biophysical Research Communications, 1989
- Physiologically-induced changes in proopiomelanocortin mRNA levels in the pituitary gland of the amphibian XenopuslaevisBiochemical and Biophysical Research Communications, 1987
- Purification and characterization of a high molecular weight proteinase (macropain) from human erythrocytesBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986