Acetylsulfanilamide. Its Absorption, Excretion and Toxicity in Man,

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Abstract
Ockerblad and Carlson gave acetylsulfanilamide (4 g. per kg. body weight) to 4 dogs and found it to produce dyspnea and a drop in the CO2-combining power. In man, acetylsulfanilamide (20 g. 4 times a day up to 2 weeks) produced slight toxic reactions or none; CO2-combining sometimes fell. Acetylsulfanilamide in man is slowly absorbed and slowly excreted. In patients with acute gonococcic urethritis acetylsulfanilamide has only a minimal degree of therapeutic effectiveness and none in chronic prostatitis.