The influence of phytic acid on the absorption of calcium and phosphorus

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Abstract
In puppies, replacement of the Ca phosphate of the diet by pentacalcium phytate, and addition of Na phytate sufficient to precipitate dietary Ca of foodstuffs, lead to decreased retention of Ca and increased retention of P. Ca retention declines with age, becoming negative when animals are about 6 mos. old. Although about 50% of the phytic acid is hydrolyzed in the intestine, it probably does not contribute to the increased retention of P, for similar increased retention of P is observed when oxalic acid is added to the diet. The retention is probably due to the increased concn. of HPO4 - ions when the Ca is precipitated by phytic acid or oxalic acid.

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