Plasma Alpha Amino- n -Butyric Acid to Leucine Ratio: An Empirical Biochemical Marker of Alcoholism

Abstract
The plasma ratio of alpha-amino-n-butyric acid to leucine was elevated in ambulatory and hospitalized alcoholics as well as in baboons fed alcohol along with an adequate diet. There was a statistically significant positive correlation between this ratio and the degree of alcoholism assessed by three separate medical and psychological criteria in patients maintained on methadone.

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