Noninvolvement of Histamine and Prostaglandins in the Dermatosis of Magnesium-Deficient Hairless Rats
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 28 (4) , 235-240
- https://doi.org/10.1159/000137968
Abstract
Hairless rats receiving a deprived Mg2+ diet developed long-lasting inflammatory dermatosis which was not influenced by treatments with mepyramine, cimetidine, aspirin or indomethacin. Dermatosis did not appear in deprived rats treated with intraperitoneal injections of Mg2+, or with dexamethasone. Histamine and prostaglandins did not seem to be involved in this dermatosis. The possible role of leucotrienes is discussed.Keywords
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