76‐kDa poly(A)—protein is involved in the formation of 48 S initiation complexes
- 27 June 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 157 (1) , 105-110
- https://doi.org/10.1016/0014-5793(83)81125-9
Abstract
In erythropoietic mouse cells induced by Friend leukemia virus, ≈50% of non‐polyribosomal globin mRNA is found in 48 S initiation complexes ready to be translated. EDTA releases 15 S globin mRNPs, homologous to polyribosomal globin mRNPs. The 76‐kDa poly(A)—protein is one of its main protein components. The other 50% of non‐polyribosomal message can be separated as 20 S ‘free’ mRNPs. Its protein composition is different, especially the 76‐kDa protein is lacking. The role of this protein is discussed.Keywords
This publication has 48 references indexed in Scilit:
- The specificity of interaction between mRNP proteins and globin mRNA in polyribosomal and cytoplasmic free mRNPFEBS Letters, 1981
- Comparisons of Proteins Associated with Duck‐Globin mRNA and Its Polyadenylated Segment in Polyribosomal and Repressed Free Messenger Ribonucleoprotein ComplexesEuropean Journal of Biochemistry, 1981
- Identification and Characterization of the Translationally Repressed Cytoplasmic Globin Messenger‐Ribonucleoprotein Particles from Duck ErythroblastsEuropean Journal of Biochemistry, 1980
- Analysis of the Population of Native 40‐S Ribosomal Subunits in Mouse Plasmacytoma Cells Grown in Suspension CultureEuropean Journal of Biochemistry, 1980
- Heterogeneity of the Nonpolysomal Cytoplasmic (Free) mRNA · protein Complexes of Embryonic Chicken MuscleEuropean Journal of Biochemistry, 1979
- Characterization of poly(A+)RNA in free messenger ribonucleoprotein and polysomes of mouse Taper ascites cellsJournal of Molecular Biology, 1979
- Specific poly-A-binding protein of 76,000 molecular weight in polyribosomes is not present on poly A of free cytoplasmic mRNPNature, 1977
- Correlation of specific coding sequences with specific proteins associated in untranslated cytoplasmic messenger ribonucleoprotein complexes of duck erFEBS Letters, 1977
- Evidence for a translational inhibitor linked to globin mRNA in untranslated free cytoplasmic messenger ribonucleoprotein complexesFEBS Letters, 1976
- Messenger RNA in HeLa Cells:European Journal of Biochemistry, 1970