Enkephalins induce asymmetrical effects on posture in the rat

Abstract
Enkephalins when applied subarachnoidally induce hind limb postural asymmetry in rats with transected spinal cord. The effect is antagonized by naloxone. Methionine-enkephalin induces predominantly left limb flexions while leucine-enkephalin causes mostly right limb flexions. The data suggest an asymmetry existing in the enkephalinergic system in the rat spinal cord.