HIV Drug Resistance

Abstract
Clavel and Hance (March 4 issue)1 review resistance to drugs used for the treatment of human immunodeficiency virus infection. Few data are available concerning patterns of antiretroviral-drug resistance among patients in developing countries. However, the fact that the expected virologic success rates of commonly used regimens containing nucleoside reverse-transcriptase inhibitors is approximately 65 percent at 48 weeks is cause for alarm.2