The offspring of marriage between two first cousins with the same reciprocal translocation t(2;7)(p11;q31)
Open Access
- 1 August 1980
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 55 (2) , 199-202
- https://doi.org/10.1007/bf00291767
Abstract
A marriage between two first cousins who have the same 2/7 balanced translocation is reported. The chromosome rearrangement was primarily detected in amniotic fluid cells cultured for prenatal chromosome analysis because of advanced maternal age. The translocation was also found in the couple's two normal children and in three other members of the family. The possible zygotic chromosome constitutions following 2:2 meiotic segregation in consanguineous parents with the same translocation are discussed.Keywords
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