The Harm Reduction Approach and Risk Factors for Human Immunodeficiency Virus (HIV) Seroconversion in Injecting Drug Users, Amsterdam

Abstract
To assess risk factors for seroconversion to human immunodeficiency virus, the authors studied a cohort of human immunodeficiency virus-seronegative injecting drug users in Amsterdam, the Netherlands, between December 1985 and November 1991. The behaviors of 31 seroconverters were compared with those of 202 seronegative injecting drug users (controls). Three independent risk factors for seroconversion were found in logistic regression: 1) living >10 years in Amsterdam (odds ratio (OR) = 2.45, 95% confidence interval (Cl) 1.09–5.53); 2) first injection Am J Epidemiol 1992;136:236–43.

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