Clonidine induced hyperphagia and weight gain in monkeys
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 61 (2) , 233-234
- https://doi.org/10.1007/bf00426742
Abstract
The effect of the α-noradrenergic receptor agonist, clonidine, on food intake and weight was examined in ten adult Stumptail macaque monkeys. An intramuscular injection of 0.1 mg/kg of clonidine HCl for seven consecutive days significantly increased food intake from baseline levels throughout treatment. All but two monkeys gained weight during clonidine treatment with seven animals gaining from 5–15% of their original body weight by the end of 1 week.Keywords
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