Serum Phenytoin Levels of Patients on Gastrostomy Tube Feeding

Publisher Website
Google Scholar
Abstract
Serum phenytoin levels of two groups of brain-injured patients on gastrostomy tube (GT) feeding were retrospectively examined. In the first group (group C = clamped, n=13), GT was clamped for one hour after the phenytoin dose (2–3 doses per day), and in the second group (group NC = not clamped, n=9) GT feedings were continued without interruption. Mean ± SD of the serum phenytoin level was 14.4 ± 4.7μg/ml for group C, and 9.2 ± 6.8 μg/ml for group NC. When serum phenytoin levels were adjusted for decreased serum albumin levels, the results were 19.8 ± 6.4 μg/ml for group C and 11.7 ± 7.9 μg/ml for group NC. Statistical analysis showed a significant difference between the means in both the phenytoin and adjusted phenytoin levels between the two groups (p

This publication has 0 references indexed in Scilit: