Electron Microscopic Characterization of Lipoproteins from Patients with Familial Type III Hyperlipoproteinaemia
- 1 February 1976
- journal article
- research article
- Published by Wiley in European Journal of Clinical Investigation
- Vol. 6 (1) , 307-310
- https://doi.org/10.1111/j.1365-2362.1976.tb00525.x
Abstract
The lipoproteins of very low density, low density and intermediate density were isolated by zonal ultracentrifugation from the plasma of subjects with familial type III hyperlipoproteinemia and studied by EM. Each of these lipoproteins exhibited a spherical shape when free-standing. The very low density, low density and intermediate density lipoproteins ranged in diameter from 31-80, 17-23 and 21-35 nm, respectively. These results are consistent with previous findings that the intermediate density lipoprotein particles characteristic of plasma from type III subjects exhibit properties which are intermediate between those of very low density and low density lipoproteins.Keywords
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