Selectivity of small intestinal exudate in celiac disease and Crohn's disease
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 23 (1) , 33-38
- https://doi.org/10.1007/bf01072572
Abstract
The small intestinal exudates of patients with protein-losing enteropathies produced by celiac disease or proximal jejunal Crohn's disease were compared with controls. The exudates in control subjects were highly selective, whereas those of the celiac and Crohn's disease subjects were relatively nonselective. It is believed that this loss of selectivity is secondary to basement membrane damage. An analogy is drawn with the renal lesion in nephrotic syndrome where basement membrane damage is associated with nonselective proteinuria.Keywords
This publication has 8 references indexed in Scilit:
- Permeability of the small intestine after intra-arterial injection of histamine-type mediators and irradiation.Gut, 1976
- Small intestinal permeability. 1. Effects of ischaemia and exposure to acetyl salicylate.Gut, 1976
- Small intestinal permeability in animals and manGut, 1973
- Plasma protein turnover (albumin, transferrin, IgG, IgM) in Menetrier's disease (giant hypertrophic gastritis): Evidence of non-selective protein lossGut, 1972
- INTESTINAL EXCRETION OF LOW AND HIGH MOLECULAR WEIGHT POLYVINYLPYRROLIDONE (PVP) IN PATIENTS WITH PROTEINURIAActa Medica Scandinavica, 1969
- D.N.A. AND CELL LOSS FROM NORMAL SMALL-INTESTINAL MUCOSAThe Lancet, 1968
- ULTRASTRUCTURE OF JEJUNAL SURFACE EPITHELIUM IN UNTREATED IDIOPATHIC STEATORRHOEABritish Medical Bulletin, 1967
- AN ELECTRON MICROSCOPIC STUDY OF ADULT CELIAC DISEASE1966