The Philadelphia Pulmonary Neoplasm Research Project

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Abstract
During a ten-year prospective study of 6,136 men, aged 45 and older, screened every six months by 70-mm photofluorograms and questionnaires, 121 men who did not have lung cancer visible on the entry film developed lung cancer; 94 cases were proved histologically. The overall survival rate was 8% at five years. From a study of various factors in the 94 proved cases, the profile of the men most likely to survive five years includes age less than the median of 64 years, smoking one pack of cigarettes per day or less, absence of chronic cough prior to detection, a histologic type of squamous cell carcinoma or adenocarcinoma, a roentgenogram of the chest negative for cancer within 12 months before detection of the cancer, and resectability of the cancer with survival longer than 30 days after surgery.

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