Maximum entropy image reconstruction of DNA sequencing gel autoradiographs
- 1 January 1990
- journal article
- research article
- Published by Wiley in Electrophoresis
- Vol. 11 (5) , 440-444
- https://doi.org/10.1002/elps.1150110515
Abstract
DNA sequencing gel autoradiographs become increasingly difficult to read as one moves up the gel, due to crowding and overlapping of the bands. Maximum entropy image reconstructions of the autoradiograph improve the ease with which crowded sequence data can be read, and extend the region of the gel in which reading is possible. Superior reconstructions are obtained by using nonuniform models based on the initial reconstructions.This publication has 12 references indexed in Scilit:
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