INFRARED-SPECTROSCOPY AND MAGNESIUM CONTENT OF BONE-MINERAL IN OSTEOPOROTIC WOMEN

  • 1 January 1981
    • journal article
    • research article
    • Vol. 17  (12) , 1123-1125
Abstract
Larger and more perfect crystals in bone mineral from osteoporotic women were described using biophysical methods. In search of the cause of this change, both chemical analysis and IR spectrophotometry were used on iliac crest bone biopsies from 19 postmenopausal osteoporotic women. These women each had a vertebral crush fracture and had a urinary hydroxyproline: creatinine ratio > 0.012. Lower than normal trabecular bone Mg content and larger and more perfect crystals in trabecular bone mineral identified on IR spectrophotometry were found in 16 out of the 19 women. Mg deficiency was confirmed by Thoren''s Mg load test in this subgroup of 16. Higher than normal bone Mg content and smaller and less perfect crystals in bone mineral were found in 5 postmenopasual uremic women tested.

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